Most medical treatments are designed for a specific disease and for the “average patient". This "one-size-fits-all-approach," may be successful for some patients but not for others. Precision medicine, sometimes known as "personalized medicine" is an innovative approach to disease prevention and treatment that takes into account differences in people’s genes, environments and lifestyles. In January 2015, President Obama launched the Precision Medicine Initiative (PMI), a bold new research effort to revolutionize how we improve health and treat disease, empowering health care providers to tailor treatment and prevention strategies to individuals’ unique characteristics. Advances in precision medicine have already led to powerful new discoveries and several new FDA-approved treatments that are tailored to specific characteristics of individuals, such as a person’s genetic makeup, or the genetic profile of an individual’s tumor. Patients with a variety of cancers routinely undergo molecular testing as part of patient care, enabling physicians to select treatments that improve chances of survival and reduce exposure to adverse effects. The PMI seeks to identify genetically-based drivers of disease in order to develop new, more effective treatments. There is a component in this equation that relates to Public Health that is very seldom discussed or incorporated into an individual’s health record: Geomedicine. This presentation will discuss how this field will change the future model of Healthcare.